No Israelis have been killed during the demonstrations, and human rights groups say the Israeli military has used live fire against demonstrators who pose no immediate threat to life.
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Israel says it is doing what it must to defend its border, and to stop any of the protesters getting across the fence.
The planned six-week protest has revived a longstanding demand for the right of return of Palestinian refugees to towns and villages from which their families fled, or were driven out, when the state of Israel was created 70 years ago.
The protest began on March 30, and is expected to culminate on May 15.